THOC1 and SAP30BP

Data Source:
BioGRID (two hybrid)

		THOC1	SAP30BP
Description		THO complex 1	SAP30 binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck	Nucleus Nucleoplasm Intermediate Filament Cytoskeleton
	Molecular Function	DNA Binding RNA Binding Protein Binding	Protein Binding
	Biological Process	Regulation Of DNA Recombination RNA Processing RNA Export From Nucleus MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing MRNA 3'-end Processing Replication Fork Processing Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of DNA Damage Checkpoint	Regulation Of Transcription, DNA-templated Apoptotic Process Positive Regulation Of Cell Death
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Height ( 31562340) Menarche (age at onset) ( 29773799) Triglyceride levels ( 32203549)	Rotator cuff tears ( 26350878)
Interacting Genes		26 interacting genes: AGR2 AKAP9 BHLHB9 CTAG1A CTAG1B DHX8 EXOC5 FRA10AC1 IK MAGEB4 MOAP1 MTNR1B NEDD4 PAX6 PPP1R12C RABGEF1 RB1 REL SAP30BP SF3B2 TADA2A TRIM27 TRIM54 USHBP1 WDR77 ZMYND12	26 interacting genes: CCNL1 CSNK2A1 DHX8 FHL2 FHL3 FRA10AC1 GOLGA2 GSK3B MLX OGT PRKAR1B PUF60 RBM17 RBM39 RPS6KA6 SAP30 SNCA SUPT5H TFIP11 THAP1 THOC1 U2AF2 WDR77 WDR83 ZNF212 ZNF408
Entrez ID		9984	29115
HPRD ID		09498	17094
Ensembl ID		ENSG00000079134	ENSG00000161526
Uniprot IDs		Q96FV9	A0A024R8R0 Q9UHR5
PDB IDs		1WXP
Enriched GO Terms of Interacting Partners?
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