CDC34 and MARCHF1

Data Source:
BioGRID (pull down)

		CDC34	MARCHF1
Description		cell division cycle 34, ubiqiutin conjugating enzyme	membrane associated ring-CH-type finger 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Speck	Cytoplasm Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane Late Endosome Membrane Trans-Golgi Network Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Zinc Ion Binding MHC Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination DNA Replication Initiation Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Cellular Response To Interferon-beta Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of CAMP-mediated Signaling Response To Growth Factor Protein K48-linked Ubiquitination Positive Regulation Of Inclusion Body Assembly	Protein Polyubiquitination Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Immune Response
Pathways		Downstream TCR signaling FCERI mediated NF-kB activation CLEC7A (Dectin-1) signaling Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		56 interacting genes: ATF5 BTRC CCNB1 CDK9 CDKN1B CREM CSNK2B CTNNB1 CUL1 CUL2 CUL3 EGFR FBXL2 FBXL3 FBXO32 FBXO4 FBXO7 FBXW2 FBXW7 HIF1A ING4 ITCH MARCHF1 MARCHF2 MDM2 MEOX1 MEOX2 MUL1 MYBL2 MYOD1 NEDD4L NEDD8 NFKBIA PPARA PPARG PRKN PTTG1 RBX1 RELA RNF31 RNF7 ROCK1 SDCBP SIAH1 SKP2 TBL1X TP53 TRIM21 TRIM28 TRIM29 UBA1 UBB VHL WWP2 ZFAND6 ZNRF1	6 interacting genes: CDC34 HLA-DRA HLA-DRB1 INSR UBE2D1 UBE2H
Entrez ID		997	55016
HPRD ID		00306	07940
Ensembl ID		ENSG00000099804	ENSG00000145416
Uniprot IDs		A0A024R1Z1 P49427	A8K0Z6 D6RGC4 Q8TCQ1
PDB IDs		2OB4 3RZ3 4MDK
Enriched GO Terms of Interacting Partners?
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