CDC34 and ING4

Data Source:
BioGRID (pull down, pull down)

		CDC34	ING4
Description		cell division cycle 34, ubiqiutin conjugating enzyme	inhibitor of growth family member 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Speck	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Intermediate Filament Cytoskeleton MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Transcription Coactivator Activity Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Polyubiquitination DNA Replication Initiation Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Cellular Response To Interferon-beta Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of CAMP-mediated Signaling Response To Growth Factor Protein K48-linked Ubiquitination Positive Regulation Of Inclusion Body Assembly	DNA Replication Protein Acetylation Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cell Cycle Arrest Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth
Pathways		Downstream TCR signaling FCERI mediated NF-kB activation CLEC7A (Dectin-1) signaling Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation	HATs acetylate histones
Drugs
Diseases
GWAS
Interacting Genes		56 interacting genes: ATF5 BTRC CCNB1 CDK9 CDKN1B CREM CSNK2B CTNNB1 CUL1 CUL2 CUL3 EGFR FBXL2 FBXL3 FBXO32 FBXO4 FBXO7 FBXW2 FBXW7 HIF1A ING4 ITCH MARCHF1 MARCHF2 MDM2 MEOX1 MEOX2 MUL1 MYBL2 MYOD1 NEDD4L NEDD8 NFKBIA PPARA PPARG PRKN PTTG1 RBX1 RELA RNF31 RNF7 ROCK1 SDCBP SIAH1 SKP2 TBL1X TP53 TRIM21 TRIM28 TRIM29 UBA1 UBB VHL WWP2 ZFAND6 ZNRF1	21 interacting genes: BEX3 CDC34 EGLN1 EP300 GRIPAP1 H3-4 H3C1 HNRNPD HOXB9 JADE2 KAT7 MAPK8IP2 MSX1 MYC NAV2 RELA SUV39H1 TLX3 TP53 TRIM55 TRIM63
Entrez ID		997	51147
HPRD ID		00306	09774
Ensembl ID		ENSG00000099804	ENSG00000111653
Uniprot IDs		A0A024R1Z1 P49427	Q9UNL4
PDB IDs		2OB4 3RZ3 4MDK	2K1J 2M1R 2PNX 2VNF 4AFL
Enriched GO Terms of Interacting Partners?
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