WASHC5 and WASHC2C

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		WASHC5	WASHC2C
Description		WASH complex subunit 5	WASH complex subunit 2C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endosome Early Endosome Endoplasmic Reticulum Cytosol Neuron Projection Neuronal Cell Body WASH Complex	Nucleolus Endosome Early Endosome Cytosol Plasma Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle WASH Complex
	Molecular Function	Protein Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding Retromer Complex Binding
	Biological Process	Oocyte Maturation Endosome Organization Lysosome Organization Positive Regulation Of Neuron Projection Development Protein Transport Endosomal Transport Actin Filament Polymerization Cellular Protein-containing Complex Localization Polar Body Extrusion After Meiotic Divisions Regulation Of Actin Nucleation Spindle Assembly Involved In Meiosis Regulation Of Vesicle Size Endosome Fission	Protein Transport Protein Localization To Endosome Retrograde Transport, Endosome To Golgi Regulation Of Substrate Adhesion-dependent Cell Spreading Retrograde Transport, Endosome To Plasma Membrane Negative Regulation Of Barbed-end Actin Filament Capping
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		2 interacting genes: WASHC1 WASHC2C	3 interacting genes: ATXN1 SUMO2 WASHC5
Entrez ID		9897	253725
HPRD ID		13786	11094
Ensembl ID		ENSG00000164961	ENSG00000172661
Uniprot IDs		E7EQI7 Q12768	A0A096LPC5 A8K5W5 B3KMC4 Q9Y4E1
PDB IDs
Enriched GO Terms of Interacting Partners?
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