WASHC5 and WASHC1

Data Source:
BioGRID (affinity chromatography technology, two hybrid, biochemical)

		WASHC5	WASHC1
Description		WASH complex subunit 5	WASH complex subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endosome Early Endosome Endoplasmic Reticulum Cytosol Neuron Projection Neuronal Cell Body WASH Complex	Exocyst Early Endosome Late Endosome Autophagosome Centriole Cytosol Early Endosome Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Recycling Endosome Membrane WASH Complex
	Molecular Function	Protein Binding	Actin Binding Protein Binding Ubiquitin Protein Ligase Binding Alpha-tubulin Binding
	Biological Process	Oocyte Maturation Endosome Organization Lysosome Organization Positive Regulation Of Neuron Projection Development Protein Transport Endosomal Transport Actin Filament Polymerization Cellular Protein-containing Complex Localization Polar Body Extrusion After Meiotic Divisions Regulation Of Actin Nucleation Spindle Assembly Involved In Meiosis Regulation Of Vesicle Size Endosome Fission	Exocytosis Negative Regulation Of Autophagy Protein Transport Endosomal Transport Extracellular Matrix Disassembly Positive Regulation Of Cell Migration Positive Regulation Of Pseudopodium Assembly Regulation Of Protein Ubiquitination Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Negative Regulation Of Phosphatidylinositol 3-kinase Activity Retrograde Transport, Endosome To Plasma Membrane
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		2 interacting genes: WASHC1 WASHC2C	54 interacting genes: ABI2 ABI3 ATPAF2 BECN1 BLOC1S2 C14orf119 C1orf216 CDR2L CEP55 EIF3F EXOC8 FHL2 GYS1 HGS HSBP1 HSF2BP IFT57 KANK2 KLC3 KRT20 KRT26 KRT28 KRT3 KRT75 KRT76 LIMK1 LMO1 LMO2 LMO3 LMO4 MORN4 MRFAP1 NDC80 NUP62CL OIP5 OSTF1 POLR1C PRKAA2 RABGEF1 RNF2 SDCBP SMARCD1 TPM1 TPM3 TRIM69 TSG101 TTC19 TXLNA UBL5 USP20 WASHC3 WASHC4 WASHC5 ZBTB16
Entrez ID		9897	100287171
HPRD ID		13786
Ensembl ID		ENSG00000164961	ENSG00000181404
Uniprot IDs		E7EQI7 Q12768	A8K0Z3
PDB IDs
Enriched GO Terms of Interacting Partners?
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