RUSC2 and RAB1B

Data Source:
HPRD (in vitro, two hybrid)

		RUSC2	RAB1B
Description		RUN and SH3 domain containing 2	RAB1B, member RAS oncogene family
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GO Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Phagophore Assembly Site Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Biological_process	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Virion Assembly Post-translational Protein Modification COPII Vesicle Coating Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Regulation Of Autophagosome Assembly
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Psoriasis ( 25903422)	Bipolar disorder ( 21926972 31043756)
Interacting Genes		9 interacting genes: DLST EGFR GIT2 GOLGA2 KHDRBS1 MAGEC1 RAB1A RAB1B SRPRA	11 interacting genes: APP CHM GDI1 GOLGA2 MICAL1 MICAL3 MICALCL RABIF RUSC2 SMARCC2 TOMM40L
Entrez ID		9853	81876
HPRD ID		18009	11469
Ensembl ID		ENSG00000198853	ENSG00000174903
Uniprot IDs		Q8N2Y8	Q9H0U4
PDB IDs		6IF2	3JZA 3NKV 4HLQ 4I1O 5O74 5SZH 5SZK 6SKU
Enriched GO Terms of Interacting Partners?
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