RUSC2 and RAB1A

Data Source:
BioGRID (two hybrid, pull down)

		RUSC2	RAB1A
Description		RUN and SH3 domain containing 2	RAB1A, member RAS oncogene family
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GO Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Extracellular Exosome	Golgi Membrane Early Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Membrane Melanosome Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding Cadherin Binding
	Biological Process	Biological_process	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Endocytosis Autophagy Golgi Organization Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Interleukin-8 Production Substrate Adhesion-dependent Cell Spreading Defense Response To Bacterium Post-translational Protein Modification Vesicle Transport Along Microtubule COPII Vesicle Coating Cilium Assembly COPII-coated Vesicle Cargo Loading Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Psoriasis ( 25903422)	High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Triglyceride levels ( 32154731)
Interacting Genes		9 interacting genes: DLST EGFR GIT2 GOLGA2 KHDRBS1 MAGEC1 RAB1A RAB1B SRPRA	28 interacting genes: ADCK1 CAPNS1 CDKN1A CHML CREB1 CSNK1D FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 OCRL PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RABIF RFK RUSC2 SLC16A8 SYT5 TBC1D17 USO1 ZNF593
Entrez ID		9853	5861
HPRD ID		18009	01538
Ensembl ID		ENSG00000198853	ENSG00000138069
Uniprot IDs		Q8N2Y8	B7Z8M7 P62820 Q5U0I6
PDB IDs		6IF2	2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS
Enriched GO Terms of Interacting Partners?
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