TOMM20 and UCP1

Data Source:
HPRD (in vitro)

		TOMM20	UCP1
Description		translocase of outer mitochondrial membrane 20	uncoupling protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Integral Component Of Mitochondrial Outer Membrane Mitochondria-associated Endoplasmic Reticulum Membrane	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding Unfolded Protein Binding	Oxidative Phosphorylation Uncoupler Activity Transmembrane Transporter Activity Purine Ribonucleotide Binding Long-chain Fatty Acid Binding Cardiolipin Binding
	Biological Process	Protein Targeting To Mitochondrion Response To Muscle Activity TRNA Import Into Mitochondrion Macroautophagy Protein Deubiquitination Protein Import Into Mitochondrial Matrix Response To 3,3',5-triiodo-L-thyronine	Diet Induced Thermogenesis Regulation Of Transcription By RNA Polymerase II Response To Temperature Stimulus Response To Cold Response To Nutrient Levels Cellular Response To Hormone Stimulus Cellular Response To Reactive Oxygen Species Brown Fat Cell Differentiation Cellular Response To Cold Cellular Response To Fatty Acid Positive Regulation Of Cold-induced Thermogenesis Proton Transmembrane Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Mitochondrial Transmembrane Transport Adaptive Thermogenesis
Pathways		Mitochondrial protein import PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases	The fatty acid cycling model The proton buffering model
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Cholesterol, total ( 20686565) Cobalt levels ( 26025379) Immune reponse to smallpox (secreted IL-2) ( 22610502) LDL cholesterol ( 20686565) LDL cholesterol levels ( 32203549) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)	Malaria ( 31844061)
Interacting Genes		19 interacting genes: AIP APOA1 ATXN1 BAG6 BCL2 CDC73 CEP126 DHFR FBXO7 FEZ1 HAP1 HSD17B10 OTC PPHLN1 PTN TOMM22 TOMM40 UCP1 VDAC1	2 interacting genes: CIDEA TOMM20
Entrez ID		9804	7350
HPRD ID		03507	00221
Ensembl ID		ENSG00000173726	ENSG00000109424
Uniprot IDs		A0A024R3W2 Q15388	P25874 Q4KMT7
PDB IDs		4APO
Enriched GO Terms of Interacting Partners?
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