UCP1 and CIDEA

Data Source:
HPRD (in vitro)

		UCP1	CIDEA
Description		uncoupling protein 1	cell death inducing DFFA like effector a
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane	Nucleus Cytoplasm Mitochondrion Mitochondrial Envelope Lipid Droplet Cytosol
	Molecular Function	Oxidative Phosphorylation Uncoupler Activity Transmembrane Transporter Activity Purine Ribonucleotide Binding Long-chain Fatty Acid Binding Cardiolipin Binding	Protein Homodimerization Activity
	Biological Process	Diet Induced Thermogenesis Regulation Of Transcription By RNA Polymerase II Response To Temperature Stimulus Response To Cold Response To Nutrient Levels Cellular Response To Hormone Stimulus Cellular Response To Reactive Oxygen Species Brown Fat Cell Differentiation Cellular Response To Cold Cellular Response To Fatty Acid Positive Regulation Of Cold-induced Thermogenesis Proton Transmembrane Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Mitochondrial Transmembrane Transport Adaptive Thermogenesis	Temperature Homeostasis Negative Regulation Of Cytokine Production Lipid Metabolic Process Apoptotic Process Cell Death Positive Regulation Of Sequestering Of Triglyceride Lipid Storage Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Production Lipid Droplet Organization Response To Stilbenoid Regulation Of Apoptotic Process Negative Regulation Of Lipid Catabolic Process Cellular Response To Cold Negative Regulation Of Cold-induced Thermogenesis Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Apoptotic DNA Fragmentation
Pathways		The fatty acid cycling model The proton buffering model	Lipid particle organization
Drugs
Diseases
GWAS		Malaria ( 31844061)	Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297)
Interacting Genes		2 interacting genes: CIDEA TOMM20	5 interacting genes: CIDEB CIDEC MIEF2 UCP1 ZBTB16
Entrez ID		7350	1149
HPRD ID		00221	08380
Ensembl ID		ENSG00000109424	ENSG00000176194
Uniprot IDs		P25874 Q4KMT7	B3KVA2 O60543 Q8N5P9
PDB IDs			2EEL
Enriched GO Terms of Interacting Partners?
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