IQCB1 and MARCHF7

Data Source:
BioGRID (pull down)

		IQCB1	MARCHF7
Description		IQ motif containing B1	membrane associated ring-CH-type finger 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Nucleoplasm Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Photoreceptor Connecting Cilium Intercellular Bridge Extracellular Exosome Mitotic Spindle	Nucleus Cytosol Plasma Membrane
	Molecular Function	Protein Binding Calmodulin Binding Enzyme Binding	Protein Binding Zinc Ion Binding Transferase Activity Ubiquitin Conjugating Enzyme Binding Ubiquitin Binding MDM2/MDM4 Family Protein Binding
	Biological Process	Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Cilium Assembly Ciliary Basal Body-plasma Membrane Docking	Regulation Of Tolerance Induction Protein Monoubiquitination Positive Regulation Of Cell Population Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Stabilization Protein Autoubiquitination Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Protein Polyubiquitination Negative Regulation Of Protein Autoubiquitination
Pathways		Anchoring of the basal body to the plasma membrane
Drugs
Diseases		Senior-Loken syndrome
GWAS		Hemoglobin levels ( 32327693) Multiple sclerosis ( 31604244 24076602) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376)
Interacting Genes		12 interacting genes: CALM2 CALML3 KIF9 LDOC1 MARCHF7 MNS1 PCMT1 PDE9A SESTD1 SMARCD1 SPG21 TRIM32	20 interacting genes: CTNNA3 EXOC8 HSF2BP IQCB1 MAPRE1 MAPRE3 MAPT PPP3CA PPP3CB RNF111 TRIM65 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2K UBE2M UBE2N USP7
Entrez ID		9657	64844
HPRD ID		11049	09817
Ensembl ID		ENSG00000173226	ENSG00000136536
Uniprot IDs		Q15051	B7Z5K0 B7ZAR7 F5H6W4 Q9H992
PDB IDs
Enriched GO Terms of Interacting Partners?
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