MARCHF7 and TRIM65

Data Source:
BioGRID (two hybrid)

		MARCHF7	TRIM65
Description		membrane associated ring-CH-type finger 7	tripartite motif containing 65
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane	Nucleoplasm Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Ubiquitin Conjugating Enzyme Binding Ubiquitin Binding MDM2/MDM4 Family Protein Binding	Zinc Ion Binding
	Biological Process	Regulation Of Tolerance Induction Protein Monoubiquitination Positive Regulation Of Cell Population Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Stabilization Protein Autoubiquitination Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Protein Polyubiquitination Negative Regulation Of Protein Autoubiquitination	Positive Regulation Of Autophagy
Pathways
Drugs
Diseases
GWAS			Body mass index ( 29273807) Deep white matter hyperintensities ( 32517579) Psoriasis ( 28537254) Reticulocyte count ( 32888494) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 21681796 25663218) White matter hyperintensity volume ( 30659137)
Interacting Genes		20 interacting genes: CTNNA3 EXOC8 HSF2BP IQCB1 MAPRE1 MAPRE3 MAPT PPP3CA PPP3CB RNF111 TRIM65 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2K UBE2M UBE2N USP7	12 interacting genes: ANAPC11 IFIH1 MARCHF7 MKRN3 RBCK1 SRPK1 TNRC6A UBE2D2 UBE2U UBE2Z UBE3A VCAM1
Entrez ID		64844	201292
HPRD ID		09817	15569
Ensembl ID		ENSG00000136536	ENSG00000141569
Uniprot IDs		B7Z5K0 B7ZAR7 F5H6W4 Q9H992	Q6PJ69
PDB IDs
Enriched GO Terms of Interacting Partners?
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