PRDX6 and SFTPA1

Data Source:
BioGRID (pull down)

		PRDX6	SFTPA1
Description		peroxiredoxin 6	surfactant protein A1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Mitochondrion Cytosol Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome	Extracellular Region Collagen Trimer Extracellular Space Multivesicular Body Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Lamellar Body Clathrin-coated Endocytic Vesicle
	Molecular Function	Glutathione Peroxidase Activity Phospholipase A2 Activity Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Cadherin Binding 1-acylglycerophosphocholine O-acyltransferase Activity Calcium-independent Phospholipase A2 Activity Peroxiredoxin Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)	Lipid Transporter Activity Protein Binding Carbohydrate Binding
	Biological Process	Response To Oxidative Stress Cellular Response To Oxidative Stress Hydrogen Peroxide Catabolic Process Neutrophil Degranulation Cell Redox Homeostasis Glycerophospholipid Catabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Cellular Oxidant Detoxification	Toll-like Receptor Signaling Pathway Lipid Transport Respiratory Gaseous Exchange By Respiratory System Opsonization Cellular Protein Metabolic Process
Pathways		Detoxification of Reactive Oxygen Species Neutrophil degranulation	Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor TLR1:TLR2 Cascade Signal regulatory protein family interactions Surfactant metabolism Regulation of TLR by endogenous ligand Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4
Drugs		2-(N-morpholino)ethanesulfonic acid Copper	2-(N-morpholino)ethanesulfonic acid
Diseases
GWAS		Adult body size ( 32376654) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Blood protein levels ( 30072576) Systemic lupus erythematosus ( 26663301) Systemic sclerosis ( 31672989)
Interacting Genes		21 interacting genes: CASP10 CASP8 GPX4 GSTP1 HNF4G MAPK1 NCF2 NR4A1 ORM2 PAXIP1 PPARD PSMD8 RARA SFTPA1 STH SUMO2 SUMO4 TERF1 TERF2IP UCHL5 YWHAE	2 interacting genes: DMBT1 PRDX6
Entrez ID		9588	653509
HPRD ID		03817	19256
Ensembl ID		ENSG00000117592	ENSG00000122852
Uniprot IDs		P30041 V9HWC7	A0A024QZP2 B4DNP6 Q8IWL2
PDB IDs		1PRX 5B6M 5B6N
Enriched GO Terms of Interacting Partners?
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