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PRDX6 and ORM2
Data Source:
BioGRID
(two hybrid)
PRDX6
ORM2
Description
peroxiredoxin 6
orosomucoid 2
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Membrane
Azurophil Granule Lumen
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Extracellular Region
Extracellular Space
Platelet Alpha Granule Lumen
Azurophil Granule Lumen
Specific Granule Lumen
Collagen-containing Extracellular Matrix
Extracellular Exosome
Blood Microparticle
Molecular Function
Glutathione Peroxidase Activity
Phospholipase A2 Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Cadherin Binding
1-acylglycerophosphocholine O-acyltransferase Activity
Calcium-independent Phospholipase A2 Activity
Peroxiredoxin Activity
Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine)
Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
Biological Process
Response To Oxidative Stress
Cellular Response To Oxidative Stress
Hydrogen Peroxide Catabolic Process
Neutrophil Degranulation
Cell Redox Homeostasis
Glycerophospholipid Catabolic Process
Positive Regulation Of MRNA Splicing, Via Spliceosome
Cellular Oxidant Detoxification
Platelet Degranulation
Regulation Of Immune System Process
Acute-phase Response
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-1 Production
Positive Regulation Of Tumor Necrosis Factor Production
Neutrophil Degranulation
Pathways
Detoxification of Reactive Oxygen Species
Neutrophil degranulation
Platelet degranulation
Neutrophil degranulation
Drugs
2-(N-morpholino)ethanesulfonic acid
Copper
Disopyramide
Lidocaine
Imipramine
Chlorpromazine
Thalidomide
Zinc
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Adult body size (
32376654
)
Asthma (age of onset) (
31036433
)
Asthma (childhood onset) (
31036433
)
Blood protein levels (
30072576
)
Systemic lupus erythematosus (
26663301
)
Systemic sclerosis (
31672989
)
Blood protein levels (
29875488
)
Interacting Genes
21 interacting genes:
CASP10
CASP8
GPX4
GSTP1
HNF4G
MAPK1
NCF2
NR4A1
ORM2
PAXIP1
PPARD
PSMD8
RARA
SFTPA1
STH
SUMO2
SUMO4
TERF1
TERF2IP
UCHL5
YWHAE
3 interacting genes:
CYP39A1
PRDX6
STK3
Entrez ID
9588
5005
HPRD ID
03817
00725
Ensembl ID
ENSG00000117592
ENSG00000228278
Uniprot IDs
P30041
V9HWC7
P19652
PDB IDs
1PRX
5B6M
5B6N
3APU
3APV
3APW
3APX
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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