MINPP1 and SOX4

Data Source:
BioGRID (two hybrid)

		MINPP1	SOX4
Description		multiple inositol-polyphosphate phosphatase 1	SRY-box transcription factor 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Extracellular Exosome	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Mitochondrion
	Molecular Function	Acid Phosphatase Activity Protein Binding Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Bisphosphoglycerate 3-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol Phosphate Phosphatase Activity Inositol Hexakisphosphate 2-phosphatase Activity Protein Histidine Phosphatase Activity	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding MiRNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Ossification Protein Dephosphorylation Polyphosphate Metabolic Process Bone Mineralization Inositol Phosphate Metabolic Process	Skeletal System Development Neural Tube Formation Pro-B Cell Differentiation Mitral Valve Morphogenesis Cardiac Ventricle Formation Cardiac Right Ventricle Morphogenesis Atrial Septum Primum Morphogenesis Noradrenergic Neuron Differentiation Regulation Of Transcription, DNA-templated DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Heart Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Glial Cell Proliferation Spinal Cord Development Spinal Cord Motor Neuron Differentiation Glial Cell Development Cell Differentiation T Cell Differentiation Endocrine Pancreas Development Negative Regulation Of Protein Ubiquitination Regulation Of Protein Stability Positive Regulation Of Insulin Secretion Somatic Stem Cell Population Maintenance Ascending Aorta Morphogenesis Glucose Homeostasis DNA Damage Response, Detection Of DNA Damage Positive Regulation Of Apoptotic Process Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Translation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Sympathetic Nervous System Development Protein Stabilization Limb Bud Formation Ventricular Septum Morphogenesis Negative Regulation Of Cell Death Neuroepithelial Cell Differentiation Kidney Morphogenesis Hematopoietic Stem Cell Homeostasis Cellular Response To Glucose Stimulus Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of N-terminal Peptidyl-lysine Acetylation
Pathways		Synthesis of IPs in the ER lumen	Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Forehead morphology ( 29921221) Longevity ( 20304771) Pursuit maintenance gain ( 29064472)	Bone mineral density ( 21533022) Cardiac hypertrophy ( 21348951) Endometrial cancer ( 30093612 27008869) Endometrial cancer (endometrioid histology) ( 30093612) Metabolite levels ( 23823483) Pulmonary function (smoking interaction) ( 23284291)
Interacting Genes		4 interacting genes: ACTA1 SOX4 SRF UBQLN2	34 interacting genes: AKT1 APOC3 AURKA CAPN15 CDKN2A CTR9 DACH1 EDF1 FOXH1 FZR1 IGF1 ITIH1 KRAS MINPP1 MNT MYC NANOGNB NF1 NF2 NSD3 PLD3 PLXNB1 RGSL1 RHOU RP1L1 SCNN1G SDCBP SMARCA4 STK11 TERT TNNI3 TSC1 UBE2I WT1
Entrez ID		9562	6659
HPRD ID		05652	01695
Ensembl ID		ENSG00000107789	ENSG00000124766
Uniprot IDs		Q9UNW1	Q06945
PDB IDs
Enriched GO Terms of Interacting Partners?
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