FXR2 and AMOTL2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FXR2	AMOTL2
Description		FMR1 autosomal homolog 2	angiomotin like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Axon Growth Cone Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Dendritic Spine Dendritic Spine Neck Presynapse Dendritic Filopodium	Cytosol Plasma Membrane Bicellular Tight Junction Cytoplasmic Vesicle Recycling Endosome
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity	Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Negative Regulation Of Translation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Positive Regulation Of Response To DNA Damage Stimulus	Angiogenesis Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Wnt Signaling Pathway Actin Cytoskeleton Organization Regulation Of Cell Migration Hippo Signaling
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737) Brain morphology (MOSTest) ( 32665545) IgM levels ( 23118916) Refractive error ( 32231278) Sex hormone-binding globulin levels ( 22675492)	Cadmium levels ( 26025379) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte fraction of red cells ( 32888494) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
Interacting Genes		107 interacting genes: AKAP9 AMOTL2 AP1M1 AP2M1 ARL6IP1 BAZ2B BLK BRCA1 BYSL C10orf62 C1orf35 CALCOCO2 CBS CCDC33 CCDC85B CCR4 CDKL3 CEP44 CEP55 COIL CWF19L2 CYFIP1 CYFIP2 DDX17 DMRTB1 DPPA2 DYNLT1 EIF4G1 EWSR1 FAM90A1 FBP1 FMR1 FTH1 FXR1 GKAP1 GTSE1 HMBOX1 HNRNPC IGFN1 INPP5J KCNRG KCTD4 KIAA1217 KIF1A KIF2A KRT20 KXD1 LASP1 LCMT1 LCP2 LDOC1 MAPRE3 MBIP MCRS1 MEAF6 MFAP1 MIA3 MORF4L1 MRPL43 NCK2 NDEL1 NDN NECAB2 NEXN NIF3L1 NME1 NONO NT5C2 PAF1 PAICS PCBD1 PCM1 PIM1 POM121 PRAM1 PRC1 PSME3 PTS RABAC1 RALYL RBBP8 RBM14 RBMX RBPMS RPIA RTN3 RTN4 SCEL SNAP23 SYT6 SYTL4 TBC1D22B THAP1 TNNT1 TRAF2 TRIM23 TRIM29 TRIM37 TSC22D4 YES1 ZBTB22 ZBTB8A ZMAT2 ZNF232 ZNF451 ZNRD2 ZSCAN1	91 interacting genes: AMOT BFSP2 BLZF1 BRMS1L BYSL CARD9 CCDC185 CCDC196 CCDC57 CCHCR1 CDC37 CDR2 CHCHD3 CINP CYTH4 DAXX DDIT3 DTNB DYNLL1 DZIP1L EIF4E2 FAM184A FAM90A1 FBXO7 FCRL5 FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KIF9 KRT1 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 L3MBTL2 LMNB2 LMO3 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MORF4L2 MPP1 MTMR6 MTNR1A MYO5B NDC80 NF2 NFIL3 NME7 NTAQ1 PIBF1 PPP2CA PPP2R1A PRKAA2 PRPF18 PSMC3 RAD51D RALBP1 RASAL3 RASSF5 RNF20 RNF40 RNF8 SAAL1 SH3RF2 SMARCE1 SOGA1 SP100 SPAG5 SPOP SPP1 TCEA2 THRA TMCC2 TNKS2 TRAF2 TRIM27 TSGA10IP YES1 ZBED1 ZBTB16 ZGPAT
Entrez ID		9513	51421
HPRD ID		05629	16485
Ensembl ID		ENSG00000129245	ENSG00000114019
Uniprot IDs		P51116	Q9Y2J4
PDB IDs		3H8Z
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?