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AMOTL2 and RAD51D
Data Source:
BioGRID
(two hybrid)
AMOTL2
RAD51D
Description
angiomotin like 2
RAD51 paralog D
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Bicellular Tight Junction
Cytoplasmic Vesicle
Recycling Endosome
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Replication Fork
Cytoplasm
Centrosome
Rad51B-Rad51C-Rad51D-XRCC2 Complex
Molecular Function
Protein Binding
Four-way Junction DNA Binding
DNA Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
Gamma-tubulin Binding
Biological Process
Angiogenesis
Establishment Of Cell Polarity Involved In Ameboidal Cell Migration
Wnt Signaling Pathway
Actin Cytoskeleton Organization
Regulation Of Cell Migration
Hippo Signaling
Telomere Maintenance Via Recombination
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
DNA Repair
Reciprocal Meiotic Recombination
Interstrand Cross-link Repair
Strand Invasion
Regulation Of Cell Cycle
Pathways
Signaling by Hippo
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange
TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases
GWAS
Cadmium levels (
26025379
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Interacting Genes
91 interacting genes:
AMOT
BFSP2
BLZF1
BRMS1L
BYSL
CARD9
CCDC185
CCDC196
CCDC57
CCHCR1
CDC37
CDR2
CHCHD3
CINP
CYTH4
DAXX
DDIT3
DTNB
DYNLL1
DZIP1L
EIF4E2
FAM184A
FAM90A1
FBXO7
FCRL5
FXR2
GCC1
GNG11
GNG5
GOLGA2
GSTM5
KIF9
KRT1
KRT13
KRT15
KRT19
KRT20
KRT31
KRT38
KRTAP10-5
KRTAP4-2
L3MBTL2
LMNB2
LMO3
LMO4
MAD1L1
MAGEA4
MAGOHB
MFAP1
MORF4L2
MPP1
MTMR6
MTNR1A
MYO5B
NDC80
NF2
NFIL3
NME7
NTAQ1
PIBF1
PPP2CA
PPP2R1A
PRKAA2
PRPF18
PSMC3
RAD51D
RALBP1
RASAL3
RASSF5
RNF20
RNF40
RNF8
SAAL1
SH3RF2
SMARCE1
SOGA1
SP100
SPAG5
SPOP
SPP1
TCEA2
THRA
TMCC2
TNKS2
TRAF2
TRIM27
TSGA10IP
YES1
ZBED1
ZBTB16
ZGPAT
49 interacting genes:
AMOTL2
BLM
C1orf94
CCDC33
CCNL1
CEP57L1
EFHC2
GEMIN4
HSF2BP
IHO1
IKZF1
IKZF3
KATNBL1
KIFC3
KRT15
LIMS1
LNX1
LZTS2
MAPK8IP3
MEOX2
NFKBID
PICK1
PNMA1
POLDIP3
PRDM14
PRDM6
RAD51B
RAD51C
RBM48
REL
RHOU
RNF138
SORBS3
SPATC1L
STX11
SWSAP1
TCF4
TEPSIN
TLE5
TRIM14
TTC23
VPS9D1
XRCC2
XRCC3
ZBTB42
ZC2HC1C
ZNF343
ZNF774
ZSWIM7
Entrez ID
51421
5892
HPRD ID
16485
04261
Ensembl ID
ENSG00000114019
ENSG00000185379
Uniprot IDs
Q9Y2J4
O75771
PDB IDs
2KZ3
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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