HOMER1 and ABI3

Data Source:
HPRD (two hybrid)

		HOMER1	ABI3
Description		homer scaffold protein 1	ABI family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Z Disc Axon Dendrite Costamere Dendritic Spine Neuron Spine Apical Part Of Cell Glutamatergic Synapse Postsynaptic Cytosol	Intracellular Anatomical Structure Cytoplasm Membrane Lamellipodium
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Signaling Adaptor Activity Ion Channel Binding	Protein Binding SH3 Domain Binding Identical Protein Binding
	Biological Process	Skeletal Muscle Contraction Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Chemical Synaptic Transmission Positive Regulation Of Signal Transduction Behavioral Response To Cocaine Skeletal Muscle Fiber Development Chemical Homeostasis Within A Tissue Protein Tetramerization Response To Calcium Ion Positive Regulation Of Calcium Ion Transport Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Calcium Ion Import Regulation Of Postsynaptic Neurotransmitter Receptor Activity Regulation Of Dendritic Spine Maintenance Regulation Of Store-operated Calcium Entry Regulation Of Cation Channel Activity	Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Blood and toenail selenium levels ( 25343990) Height ( 18193045) Hepcidin/ferritin ratio ( 27846281) Lateral ventricle temporal horn volume ( 31530798) Major depressive disorder ( 20673876) Metabolite levels ( 23823483) Toenail selenium levels ( 25343990)	Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		34 interacting genes: ABI1 ABI3 AGAP2 AIMP1 BRME1 C1orf116 CENPQ DBNL DNM3 EFNB2 FAM9A FAT1 FCHSD2 GRIA1 GRIK1 GRM1 GRM5 HOMER3 ITPR1 NUP54 PATJ PIAS2 RAD54L2 RASAL3 RYR1 RYR2 SHANK1 SHANK2 STX12 SYCE2 TANC1 TRAF5 TRPC1 ZMYM5	77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1
Entrez ID		9456	51225
HPRD ID		09211	05900
Ensembl ID		ENSG00000152413	ENSG00000108798
Uniprot IDs		Q5U5K4 Q86YM7	Q9P2A4
PDB IDs
Enriched GO Terms of Interacting Partners?
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