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HOMER1 and AGAP2
Data Source:
BioGRID
(affinity chromatography technology, pull down)
HPRD
(in vivo, in vitro)
HOMER1
AGAP2
Description
homer scaffold protein 1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Postsynaptic Density
Z Disc
Axon
Dendrite
Costamere
Dendritic Spine
Neuron Spine
Apical Part Of Cell
Glutamatergic Synapse
Postsynaptic Cytosol
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Cytosol
Membrane
Extracellular Exosome
Flemming Body
Molecular Function
Protein Binding
G Protein-coupled Glutamate Receptor Binding
Signaling Adaptor Activity
Ion Channel Binding
GTPase Activity
GTPase Activator Activity
Protein Binding
ATP Binding
GTP Binding
Protein Kinase Binding
Protein Kinase Activator Activity
Phosphatidylinositol 3-kinase Regulator Activity
Metal Ion Binding
Biological Process
Skeletal Muscle Contraction
Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway
G Protein-coupled Glutamate Receptor Signaling Pathway
Chemical Synaptic Transmission
Positive Regulation Of Signal Transduction
Behavioral Response To Cocaine
Skeletal Muscle Fiber Development
Chemical Homeostasis Within A Tissue
Protein Tetramerization
Response To Calcium Ion
Positive Regulation Of Calcium Ion Transport
Regulation Of Synaptic Transmission, Glutamatergic
Regulation Of Calcium Ion Import
Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Regulation Of Dendritic Spine Maintenance
Regulation Of Store-operated Calcium Entry
Regulation Of Cation Channel Activity
Protein Transport
Endosomal Transport
Actin Cytoskeleton Organization
Activation Of Protein Kinase Activity
Negative Regulation Of Protein Catabolic Process
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of GTPase Activity
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of 1-phosphatidylinositol-3-kinase Activity
Pathways
Neurexins and neuroligins
Neurexins and neuroligins
Netrin-1 signaling
Drugs
Diseases
GWAS
Bipolar disorder (
31043756
)
Blood and toenail selenium levels (
25343990
)
Height (
18193045
)
Hepcidin/ferritin ratio (
27846281
)
Lateral ventricle temporal horn volume (
31530798
)
Major depressive disorder (
20673876
)
Metabolite levels (
23823483
)
Toenail selenium levels (
25343990
)
Heel bone mineral density (
30598549
)
Multiple sclerosis (
21833088
)
Interacting Genes
34 interacting genes:
ABI1
ABI3
AGAP2
AIMP1
BRME1
C1orf116
CENPQ
DBNL
DNM3
EFNB2
FAM9A
FAT1
FCHSD2
GRIA1
GRIK1
GRM1
GRM5
HOMER3
ITPR1
NUP54
PATJ
PIAS2
RAD54L2
RASAL3
RYR1
RYR2
SHANK1
SHANK2
STX12
SYCE2
TANC1
TRAF5
TRPC1
ZMYM5
13 interacting genes:
AKT1
ARF1
CDC42
EPB41L1
GRIP1
HOMER1
HOMER2
NF2
PIK3R1
PLCG1
RAC1
RAC2
RHOA
Entrez ID
9456
116986
HPRD ID
09211
05687
Ensembl ID
ENSG00000152413
ENSG00000135439
Uniprot IDs
Q5U5K4
Q86YM7
A0A024RB55
F8VVT9
Q99490
PDB IDs
2BMJ
2IWR
2RLO
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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