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MED7 and SREBF1
Data Source:
BioGRID
(pull down, biochemical, affinity chromatography technology)
MED7
SREBF1
Description
mediator complex subunit 7
sterol regulatory element binding transcription factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleoplasm
Transcription Regulator Complex
Mediator Complex
Nuclear Body
Golgi Membrane
Chromatin
Nucleus
Nuclear Envelope
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
ER To Golgi Transport Vesicle Membrane
Integral Component Of Membrane
Protein-containing Complex
Molecular Function
Transcription Coactivator Activity
Protein Binding
Ubiquitin Protein Ligase Activity
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Nuclear Receptor Activity
Protein Binding
Protein Kinase Binding
Sterol Response Element Binding
Protein-containing Complex Binding
Protein Dimerization Activity
Sequence-specific Double-stranded DNA Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Protein Ubiquitination
Stem Cell Population Maintenance
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Heart Rate By Chemical Signal
Regulation Of Transcription By RNA Polymerase II
Lipid Metabolic Process
Aging
Circadian Rhythm
Cholesterol Metabolic Process
Insulin Receptor Signaling Pathway
Lipid Biosynthetic Process
Cellular Response To Starvation
Response To Glucose
Positive Regulation Of Triglyceride Biosynthetic Process
Lipid Localization
Regulation Of Lipid Storage
Regulation Of Fatty Acid Metabolic Process
Lung Development
Intracellular Receptor Signaling Pathway
Positive Regulation Of Histone Deacetylation
Regulation Of Protein Stability
Response To Food
Response To Retinoic Acid
Response To Progesterone
SREBP Signaling Pathway
Response To Glucagon
Response To Drug
MRNA Transcription By RNA Polymerase II
Fat Cell Differentiation
Response To Ethanol
Regulation Of Cholesterol Biosynthetic Process
Positive Regulation Of Cholesterol Biosynthetic Process
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Insulin Secretion
Response To CAMP
Cellular Response To Fatty Acid
Regulation Of Autophagy Of Mitochondrion
Regulation Of Protein Targeting To Mitochondrion
Pathways
PPARA activates gene expression
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Transcriptional regulation of white adipocyte differentiation
RORA activates gene expression
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs
Doconexent
Omega-3-acid ethyl esters
Omega-3 fatty acids
Fish oil
Diseases
GWAS
Medication use (thyroid preparations) (
31015401
)
Coffee consumption (
31046077
)
Eosinophil counts (
32888494
)
Lymphocyte counts (
32888494
)
Monocyte count (
32888494
)
Parkinson's disease (
21738487
)
Resting heart rate (
27798624
)
Schizophrenia (
28991256
25056061
29483656
)
TB-LM or TBLH-BMD (pleiotropy) (
28743860
)
White blood cell count (
32888494
)
Interacting Genes
23 interacting genes:
CAB39
CTDP1
DNMT3L
ESR1
ESR2
HAUS1
HGS
HNF4A
IKBKG
LZTR1
MED31
MED8
MED9
PCBD2
PML
RBFOX2
RELA
RHOXF2
SREBF1
TRIM15
TRIM29
UBE2I
ZSCAN1
40 interacting genes:
AR
ATXN1
ATXN1L
CDK8
CREBBP
EP300
ESR1
ESR2
FBXW7
GSK3B
HNF4A
ID2
ID3
KLF13
LMNA
MAPK1
MAPK3
MED1
MED12
MED13
MED14
MED17
MED23
MED24
MED25
MED26
MED6
MED7
MTNR1B
NR0B1
NR5A2
PLK1
PRMT5
SMARCD3
SP1
SUMO1
TWIST2
UBE2I
YY1
ZBTB7C
Entrez ID
9443
6720
HPRD ID
05439
01701
Ensembl ID
ENSG00000155868
ENSG00000072310
Uniprot IDs
O43513
Q6IAZ5
A8MTU8
B3KR77
P36956
PDB IDs
1AM9
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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