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TMPRSS11D and ACE2
Data Source:
BioGRID
(enzymatic study)
TMPRSS11D
ACE2
Description
transmembrane serine protease 11D
angiotensin converting enzyme 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Integral Component Of Plasma Membrane
Extracellular Exosome
Extracellular Region
Extracellular Space
Cytoplasm
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Apical Plasma Membrane
Brush Border Membrane
Membrane Raft
Extracellular Exosome
Molecular Function
Serine-type Endopeptidase Activity
Protein Binding
Peptidase Activity
Virus Receptor Activity
Endopeptidase Activity
Carboxypeptidase Activity
Metallocarboxypeptidase Activity
Protein Binding
Metallopeptidase Activity
Peptidyl-dipeptidase Activity
Zinc Ion Binding
Biological Process
Proteolysis
Respiratory Gaseous Exchange By Respiratory System
Regulation Of Cytokine Production
Angiotensin Maturation
Angiotensin-mediated Drinking Behavior
Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin
Tryptophan Transport
Regulation Of Vasoconstriction
Regulation Of Transmembrane Transporter Activity
Regulation Of Cell Population Proliferation
Viral Entry Into Host Cell
Receptor-mediated Virion Attachment To Host Cell
Regulation Of Inflammatory Response
Positive Regulation Of Amino Acid Transport
Positive Regulation Of Cardiac Muscle Contraction
Blood Vessel Diameter Maintenance
Positive Regulation Of Gap Junction Assembly
Regulation Of Cardiac Conduction
Positive Regulation Of L-proline Import Across Plasma Membrane
Negative Regulation Of Signaling Receptor Activity
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Metabolism of Angiotensinogen to Angiotensins
Attachment and Entry
Potential therapeutics for SARS
Attachment and Entry
Attachment and Entry
Drugs
Chloroquine
Hydroxychloroquine
SPP1148
N-(2-Aminoethyl)-1-aziridineethanamine
Diseases
GWAS
Metabolite levels (
23823483
)
Regular attendance at a pub or social club (
29970889
)
Venous thromboembolism adjusted for sickle cell variant rs77121243-T (
28203683
)
Interacting Genes
2 interacting genes:
ACE2
SGTA
12 interacting genes:
AGT
CALM1
DEFA5
DLEU2
GHRL
NTS
PDZK1
SHANK1
SLC6A19
SNX17
TMPRSS11A
TMPRSS11D
Entrez ID
9407
59272
HPRD ID
05642
02274
Ensembl ID
ENSG00000153802
ENSG00000130234
Uniprot IDs
B4DL57
O60235
Q9BYF1
PDB IDs
1R42
1R4L
1XJP
2AJF
3D0G
3D0H
3D0I
3KBH
3SCI
3SCJ
3SCK
3SCL
6ACG
6ACJ
6ACK
6CS2
6LZG
6M0J
6M17
6M18
6M1D
6VW1
7A91
7A92
7A94
7A95
7A96
7A97
7A98
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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