Wiki-Pi
About
Search
Browse
People
Updates
Search
ACE2 and DEFA5
Data Source:
BioGRID
(pull down)
ACE2
DEFA5
Description
angiotensin converting enzyme 2
defensin alpha 5
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Apical Plasma Membrane
Brush Border Membrane
Membrane Raft
Extracellular Exosome
Extracellular Region
Extracellular Space
Golgi Lumen
Transport Vesicle
Midbody
Secretory Granule Lumen
Intracellular Membrane-bounded Organelle
Molecular Function
Virus Receptor Activity
Endopeptidase Activity
Carboxypeptidase Activity
Metallocarboxypeptidase Activity
Protein Binding
Metallopeptidase Activity
Peptidyl-dipeptidase Activity
Zinc Ion Binding
Protein Binding
Protein Homodimerization Activity
Biological Process
Regulation Of Cytokine Production
Angiotensin Maturation
Angiotensin-mediated Drinking Behavior
Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin
Tryptophan Transport
Regulation Of Vasoconstriction
Regulation Of Transmembrane Transporter Activity
Regulation Of Cell Population Proliferation
Viral Entry Into Host Cell
Receptor-mediated Virion Attachment To Host Cell
Regulation Of Inflammatory Response
Positive Regulation Of Amino Acid Transport
Positive Regulation Of Cardiac Muscle Contraction
Blood Vessel Diameter Maintenance
Positive Regulation Of Gap Junction Assembly
Regulation Of Cardiac Conduction
Positive Regulation Of L-proline Import Across Plasma Membrane
Negative Regulation Of Signaling Receptor Activity
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Innate Immune Response In Mucosa
Antimicrobial Humoral Response
Antibacterial Humoral Response
Killing Of Cells Of Other Organism
Innate Immune Response
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Defense Response To Fungus
Membrane Disruption In Other Organism
Killing By Host Of Symbiont Cells
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cellular Response To Lipopolysaccharide
Positive Regulation Of Membrane Permeability
Pathways
Metabolism of Angiotensinogen to Angiotensins
Attachment and Entry
Potential therapeutics for SARS
Attachment and Entry
Attachment and Entry
Defensins
Alpha-defensins
Drugs
Chloroquine
Hydroxychloroquine
SPP1148
N-(2-Aminoethyl)-1-aziridineethanamine
Diseases
GWAS
Basophil count (
32888494
)
Blood protein levels (
30072576
)
Cerebrospinal fluid p-Tau181p:AB1-42 ratio (
26252872
)
Mercury levels (
26025379
)
Interacting Genes
12 interacting genes:
AGT
CALM1
DEFA5
DLEU2
GHRL
NTS
PDZK1
SHANK1
SLC6A19
SNX17
TMPRSS11A
TMPRSS11D
4 interacting genes:
ACE2
DTX1
MEOX2
PRSS1
Entrez ID
59272
1670
HPRD ID
02274
02720
Ensembl ID
ENSG00000130234
ENSG00000164816
Uniprot IDs
Q9BYF1
Q01523
PDB IDs
1R42
1R4L
1XJP
2AJF
3D0G
3D0H
3D0I
3KBH
3SCI
3SCJ
3SCK
3SCL
6ACG
6ACJ
6ACK
6CS2
6LZG
6M0J
6M17
6M18
6M1D
6VW1
7A91
7A92
7A94
7A95
7A96
7A97
7A98
1ZMP
2LXZ
2MIT
3I5W
4E82
4E83
4E86
4RBW
4RBX
5CUI
5CUJ
5CUM
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?