TTYH2 and COPB1

Data Source:
BioGRID (two hybrid)

		TTYH2	COPB1
Description		tweety family member 2	COPI coat complex subunit beta 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Chloride Channel Complex	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane COPI Vesicle Coat Transport Vesicle Secretory Granule Membrane Intracellular Membrane-bounded Organelle Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Intracellular Calcium Activated Chloride Channel Activity Protein Binding Volume-sensitive Chloride Channel Activity	Structural Molecule Activity Protein Binding
	Biological Process	Chloride Transmembrane Transport	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Viral Process Neutrophil Degranulation
Pathways		Stimuli-sensing channels	Neutrophil degranulation COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Systolic blood pressure (cigarette smoking interaction) ( 26752167)	HDL cholesterol ( 26780889) HDL cholesterol levels ( 32203549 28334899) Height ( 31562340) High chromosomal aberration frequency (total) ( 31586183) Vitamin D levels ( 25208829)
Interacting Genes		15 interacting genes: CCND2 CDKN2B COPB1 ERBB2 FGFR4 GPR37 GRM1 IGF1R IKBKG KAT2A KDELR2 NEDD4 NF2 PDGFRA TRARG1	44 interacting genes: ADAM19 APP ARCN1 ARF1 BCAR1 COPE COPG1 COPG2 ERBIN FOXB1 GORAB GRB2 GTPBP4 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 KIAA1328 LINC00839 LZTS1 LZTS2 NUB1 PDGFRB PRKCE PTEN RGS2 RGS4 RHOQ SCYL1 SERTAD1 SNTA1 SPTBN1 TANK TAPBP TMED10 TRIM37 TTYH2 UBC UBQLN4 VPS18 WBP2 XRCC6
Entrez ID		94015	1315
HPRD ID		16394	02981
Ensembl ID		ENSG00000141540	ENSG00000129083
Uniprot IDs		B4DKD1 Q8N3U8 Q9BSA4	P53618
PDB IDs
Enriched GO Terms of Interacting Partners?
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