KCNG4 and KCNE5

Data Source:
BioGRID (fluorescent resonance energy transfer)

		KCNG4	KCNE5
Description		potassium voltage-gated channel modifier subfamily G member 4	potassium voltage-gated channel subfamily E regulatory subunit 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Ion Channel Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Ion Channel Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Regulation Of Heart Contraction Cardiac Muscle Contraction Regulation Of Membrane Repolarization Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Atrial Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Cation Channel Activity
Pathways		Voltage gated Potassium channels	Phase 3 - rapid repolarisation Phase 2 - plateau phase
Drugs		Enflurane Promethazine Miconazole	Enflurane Promethazine Miconazole
Diseases
GWAS		Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		4 interacting genes: KCNB1 KCNB2 KCNE5 KCNF1	7 interacting genes: APP GET3 KCNB1 KCNG4 PGRMC1 SGTA SGTB
Entrez ID		93107	23630
HPRD ID		16253	02268
Ensembl ID		ENSG00000168418	ENSG00000176076
Uniprot IDs		Q32MC1 Q547S7 Q8TDN1	Q9UJ90
PDB IDs
Enriched GO Terms of Interacting Partners?
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