KCNE5 and KCNG4

Data Source:
BioGRID (fluorescent resonance energy transfer)

		KCNE5	KCNG4
Description		potassium voltage-gated channel subfamily E regulatory subunit 5	potassium voltage-gated channel modifier subfamily G member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Ion Channel Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Ion Channel Binding
	Biological Process	Regulation Of Heart Contraction Cardiac Muscle Contraction Regulation Of Membrane Repolarization Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Atrial Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Cation Channel Activity	Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways		Phase 3 - rapid repolarisation Phase 2 - plateau phase	Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole	Enflurane Promethazine Miconazole
Diseases
GWAS			Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		7 interacting genes: APP GET3 KCNB1 KCNG4 PGRMC1 SGTA SGTB	4 interacting genes: KCNB1 KCNB2 KCNE5 KCNF1
Entrez ID		23630	93107
HPRD ID		02268	16253
Ensembl ID		ENSG00000176076	ENSG00000168418
Uniprot IDs		Q9UJ90	Q32MC1 Q547S7 Q8TDN1
PDB IDs
Enriched GO Terms of Interacting Partners?
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