CD8A and CACYBP

Data Source:
BioGRID (two hybrid)

		CD8A	CACYBP
Description		CD8a molecule	calcyclin binding protein
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane T Cell Receptor Complex Plasma Membrane Raft	Nucleus Nuclear Envelope Lumen Nucleoplasm Cytosol SCF Ubiquitin Ligase Complex Beta-catenin Destruction Complex Neuron Projection Cell Body Extracellular Exosome
	Molecular Function	Protein Binding Coreceptor Activity MHC Class I Protein Complex Binding MHC Class I Protein Binding	Protein Binding Tubulin Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity S100 Protein Binding
	Biological Process	T Cell Mediated Immunity Immune Response Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Antigen Processing And Presentation T Cell Activation Cytotoxic T Cell Differentiation Regulation Of Immune Response	Heart Development Aging Positive Regulation Of DNA Replication Cardiac Muscle Cell Differentiation Response To Growth Hormone Negative Regulation Of Cell Death Cellular Response To Calcium Ion Cellular Response To Leukemia Inhibitory Factor
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases		Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS		Blood protein levels ( 30072576)
Interacting Genes		17 interacting genes: B2M CACYBP CD3D CD59 CD8B CDK1 HLA-A HLA-B HLA-C HLA-E HLA-G LAT LCK LGALS1 PTPRC SREK1 SRSF1	20 interacting genes: BEX3 CCR2 CD8A ERBB2 FBXO7 HSP90AA1 HSP90B1 MAPK1 NPM1 PEA15 PINX1 PRKCA S100A1 S100A12 S100A6 S100B S100P SIAH1 SIAH2 SKP1
Entrez ID		925	27101
HPRD ID		01737	07316
Ensembl ID		ENSG00000153563	ENSG00000116161
Uniprot IDs		P01732 Q6ZVS2 Q8TAW8	A0A024R904 Q9HB71
PDB IDs		1AKJ 1CD8 1Q69 2HP4 3QZW	1X5M 2A25 2A26
Enriched GO Terms of Interacting Partners?
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