LRRFIP1 and CEP44

Data Source:
BioGRID (two hybrid)

		LRRFIP1	CEP44
Description		LRR binding FLII interacting protein 1	centrosomal protein 44
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane	Spindle Pole Cytoplasm Centrosome Centriole Midbody
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Double-stranded RNA Binding Protein Binding Protein Homodimerization Activity Cadherin Binding	Protein Binding Microtubule Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Type I Interferon Production Positive Regulation Of NF-kappaB Transcription Factor Activity	Centrosome Cycle Centriole Replication Centriole-centriole Cohesion
Pathways		Signaling by cytosolic FGFR1 fusion mutants LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Signaling by FGFR1 in disease
Drugs
Diseases
GWAS		Adiposity ( 23505185) Apolipoprotein A1 levels ( 32203549) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Longevity ( 30294719)
Interacting Genes		6 interacting genes: CEP44 FBXO7 FLII MED4 SERPINB5 SH2D2A	54 interacting genes: ABI2 ABI3 ANKRD11 AQP1 BEND7 BFSP2 BLOC1S6 BYSL CAB39 CBY2 CCDC116 CCDC146 CCDC185 CDC23 CENPP CEP57L1 CHIC2 DCTN2 DHX57 DIP2A ERAL1 FAM161A FAM74A4 FXR2 GNG11 H2AP HAUS1 ING5 KIAA0930 LINC02363 LMO1 LRRFIP1 MAPK9 MCRS1 MLLT6 MRFAP1L1 NAA10 PLEKHF2 POLR3C POP5 PSMD3 RBM15 RECK RNF8 SCNM1 TCEA2 TRIM41 TSGA10 TXLNA ZFYVE26 ZNF250 ZNF417 ZNF587 ZNF688
Entrez ID		9208	80817
HPRD ID		04460	13885
Ensembl ID		ENSG00000124831	ENSG00000164118
Uniprot IDs		A0A0F7NGI8 B4DPC0 Q32MZ4	Q9C0F1
PDB IDs		4H22
Enriched GO Terms of Interacting Partners?
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