LRRFIP1

Description		LRR binding FLII interacting protein 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Double-stranded RNA Binding Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Type I Interferon Production Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Signaling by cytosolic FGFR1 fusion mutants LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Signaling by FGFR1 in disease
Drugs
Diseases
GWAS		Adiposity ( 23505185) Apolipoprotein A1 levels ( 32203549) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Longevity ( 30294719)
Novel Interacting Genes		1 novel interacting genes: AP2B1
Interacting Genes		6 interacting genes: CEP44 FBXO7 FLII MED4 SERPINB5 SH2D2A
Entrez ID		9208
HPRD ID		04460
Ensembl ID		ENSG00000124831
Uniprot IDs		A0A0F7NGI8 B4DPC0 Q32MZ4
PDB IDs		4H22
Enriched GO Terms of Interacting Partners?
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