AP4M1 and LAMP2

Data Source:
HPRD (in vitro)

		AP4M1	LAMP2
Description		adaptor related protein complex 4 subunit mu 1	lysosomal associated membrane protein 2
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GO Annotations	Cellular Component	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Extracellular Space Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Membrane Phagocytic Vesicle Membrane Platelet Dense Granule Membrane Late Endosome Membrane Azurophil Granule Membrane Lysosomal Lumen Autolysosome Membrane Raft Extracellular Exosome Integral Component Of Autophagosome Membrane Membrane Microdomain Ficolin-1-rich Granule Membrane Lysosomal Matrix
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding Enzyme Binding Protein Domain Specific Binding
	Biological Process	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Endosome Transport Protein Localization Vesicle-mediated Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane	Platelet Degranulation Protein Targeting Cellular Response To Starvation Protein Import Regulation Of Protein Stability Neutrophil Degranulation Muscle Cell Cellular Homeostasis Protein Stabilization Chaperone-mediated Autophagy Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Establishment Of Protein Localization To Organelle Autophagosome Maturation Lysosomal Protein Catabolic Process
Pathways		Lysosome Vesicle Biogenesis	Platelet degranulation Neutrophil degranulation Chaperone Mediated Autophagy
Drugs
Diseases		Cerebral palsy	Danon disease; X-linked vacuolar cardiomyopathy and myopathy
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		14 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22	5 interacting genes: AP4M1 APLNR CTSA PIAS4 UCHL1
Entrez ID		9179	3920
HPRD ID		03803	02396
Ensembl ID		ENSG00000221838	ENSG00000005893
Uniprot IDs		C9JC87 O00189	P13473
PDB IDs		3L81 4MDR	2MOF 2MOM
Enriched GO Terms of Interacting Partners?
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