AQP10 and SYT2

Data Source:
BioGRID (two hybrid)

		AQP10	SYT2
Description		aquaporin 10	synaptotagmin 2
Image			No pdb structure
GO Annotations	Cellular Component	Lipid Droplet Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Intracellular Membrane-bounded Organelle	Plasma Membrane Integral Component Of Membrane Axon Clathrin-coated Vesicle Membrane Synaptic Vesicle Membrane Dense Core Granule Chromaffin Granule Membrane Exocytic Vesicle
	Molecular Function	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding Inositol 1,3,4,5 Tetrakisphosphate Binding
	Biological Process	Water Transport Response To Toxic Substance Glycerol Transport Protein Homotetramerization Cellular Response To Acidic PH Urea Transmembrane Transport	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Cell Differentiation Synaptic Vesicle Endocytosis Calcium Ion-regulated Exocytosis Of Neurotransmitter Membrane Organization Cellular Response To Calcium Ion Positive Regulation Of Dendrite Extension
Pathways		Passive transport by Aquaporins	Toxicity of botulinum toxin type B (botB) Neurexins and neuroligins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs			Botulinum Toxin Type B
Diseases
GWAS		Bipolar disorder ( 31043756) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Non-albumin protein levels ( 29403010) Parkinson's disease progression (motor) ( 33111402) Red cell distribution width ( 32888494) Serum total protein level ( 29403010)	Celiac disease ( 23936387) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		20 interacting genes: ARL13B CISD2 CREB3L1 CYBC1 ERGIC3 GPR152 GPR37L1 KIR2DL3 LMNA LYVE1 MGST3 NEMP1 PGRMC2 PLP1 PVR SAR1A SCN3B SSMEM1 SYT2 TMEM167B	29 interacting genes: AQP10 BNIP2 CCDC167 CLDN4 CMTM3 FA2H FUNDC2 ITGAM KLHL3 LAT MALL MIP NAPB NRXN1 ORMDL3 PLPP4 PMP22 SLC30A8 SLC35A1 SLC35A4 STON2 SYNCRIP TF THSD7B TMEM107 TMEM229B TSPO2 VAMP4 WNK1
Entrez ID		89872	127833
HPRD ID		07361	02520
Ensembl ID		ENSG00000143595	ENSG00000143858
Uniprot IDs		Q96PS8	Q8N9I0
PDB IDs		6F7H
Enriched GO Terms of Interacting Partners?
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