TRIM24 and TAF11

Data Source:
BioGRID (enzymatic study)
HPRD (in vitro)

		TRIM24	TAF11
Description		tripartite motif containing 24	TATA-box binding protein associated factor 11
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GO Annotations	Cellular Component	Euchromatin Nucleus Nucleoplasm Perichromatin Fibrils Cytosol	Nucleoplasm Transcription Factor TFIID Complex Golgi Apparatus
	Molecular Function	P53 Binding Chromatin Binding Transcription Coactivator Activity Protein Kinase Activity Signaling Receptor Binding Protein Binding Zinc Ion Binding Nuclear Receptor Binding Estrogen Response Element Binding Methylated Histone Binding Ubiquitin Protein Ligase Activity Lysine-acetylated Histone Binding	Transcription Coactivator Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity Protein N-terminus Binding
	Biological Process	Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Protein Ubiquitination Protein Catabolic Process Regulation Of Protein Stability Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Calcium Ion Homeostasis Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Regulation Of Signal Transduction By P53 Class Mediator	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter SnRNA Transcription By RNA Polymerase II Positive Regulation By Host Of Viral Transcription Positive Regulation Of Transcription, DNA-templated RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Signaling by BRAF and RAF fusions	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Quantitative traits ( 19197348)
Interacting Genes		49 interacting genes: AR ATF4 BRCA1 BRD7 CBX1 CBX3 CBX5 ESR1 ESR2 FOSL1 GTF2E1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 HNF4A HSPA1A HSPB1 MTNR1B NFE2L2 NR2F2 NR3C1 NR3C2 PGR PML PPARG RARA RNF141 RNF181 RXRA STAT6 SUMO1 TAF11 TAF1B TAF1C TAF7 THRA TRIM28 TRIM33 TRIM8 UBE2I UBE2U VDR ZNF10	28 interacting genes: APP APPBP2 CPSF1 GTF2B GTF2E1 GTF2F1 H3-4 LZTR1 NFYA NFYB NFYC RELA RXRA RXRB TAF1 TAF10 TAF12 TAF13 TAF2 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP TRIM24 VDR
Entrez ID		8805	6882
HPRD ID		04556	15980
Ensembl ID		ENSG00000122779	ENSG00000064995
Uniprot IDs		A0A024R784 O15164	Q15544
PDB IDs		2YYN 3O33 3O34 3O35 3O36 3O37 4YAB 4YAD 4YAT 4YAX 4YBM 4YBS 4YBT 4YC9 4ZQL 5H1T 5H1U 5H1V	1BH8 1BH9 6MZD 6MZL
Enriched GO Terms of Interacting Partners?
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