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SNX4 and SUPT5H
Data Source:
BioGRID
(two hybrid)
SNX4
SUPT5H
Description
sorting nexin 4
SPT5 homolog, DSIF elongation factor subunit
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytoplasmic Dynein Complex
Plasma Membrane
Membrane
SNARE Complex
Early Endosome Membrane
Protein-containing Complex
Nucleus
Nucleoplasm
DSIF Complex
Molecular Function
Epidermal Growth Factor Receptor Binding
Insulin Receptor Binding
Protein Binding
Phosphatidylinositol Binding
Transferrin Receptor Binding
Leptin Receptor Binding
Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
Enzyme Binding
Protein Heterodimerization Activity
Biological Process
Protein Transport
Endocytic Recycling
Positive Regulation Of Histamine Secretion By Mast Cell
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Positive Regulation Of Macroautophagy
Negative Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Viral Transcription
Negative Regulation Of MRNA Polyadenylation
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
RNA Polymerase II Transcription Elongation
RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Urate levels (
31578528
)
Neutrophil count (
32888494
)
White blood cell count (
32888494
)
Interacting Genes
18 interacting genes:
AGK
ARL6IP1
ATP6V0A1
BIN1
DGAT2L6
EGFR
HIVEP1
INSR
LEPR
MAGEA6
PDGFRA
PDGFRB
PTPN5
SH3GLB1
SNX2
SNX6
SNX7
SUPT5H
45 interacting genes:
C9orf78
CCNH
CCNT1
CCNT2
CDK7
CDK9
CEP55
CSNK2A1
DBN1
DCAF6
FHL3
GOLGA2
GTF3C1
H2AX
HSPB1
HTATSF1
IK
IKBKG
LMAN2
MAD1L1
MAML3
MNAT1
PCBD1
PHYHIP
PIN1
PNO1
POLR2A
PPIA
PPP2R2D
PRMT1
PRMT5
SAP30BP
SIK1
SNX4
SSBP3
SUMO2
SUPT4H1
TERF1
TEX11
TLE5
XRCC5
ZBTB3
ZFYVE9
ZNF496
ZNF512B
Entrez ID
8723
6829
HPRD ID
09334
03655
Ensembl ID
ENSG00000114520
ENSG00000196235
Uniprot IDs
O95219
O00267
PDB IDs
2DO3
2E6Z
2E70
3H7H
4L1U
5OHO
5OHQ
5OIK
5U98
6EQY
6ER0
6GMH
6GML
6TED
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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