RFXANK and RFX5

Data Source:
HPRD (in vivo)

		RFXANK	RFX5
Description		regulatory factor X associated ankyrin containing protein	regulatory factor X5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Intercellular Bridge RNA Polymerase II Transcription Regulator Complex	Chromatin RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Histone Deacetylase Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Ras Protein Signal Transduction Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Bare lymphocyte syndrome (BLS) type2 Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency	Bare lymphocyte syndrome (BLS) type2 Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Refractive error ( 32231278)	Body mass index ( 26426971)
Interacting Genes		6 interacting genes: CIITA HDAC4 HDAC5 RAF1 RFX5 RFXAP	5 interacting genes: APP CIITA HDAC2 RFXANK RFXAP
Entrez ID		8625	5993
HPRD ID		04435	03517
Ensembl ID		ENSG00000064490	ENSG00000143390
Uniprot IDs		A0A024R7M1 A0A024R7P0 O14593	P48382
PDB IDs		3UXG 3V30 6MEW	2KW3 3V30
Enriched GO Terms of Interacting Partners?
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