RFX5 and RFXANK

Data Source:
HPRD (in vivo)

		RFX5	RFXANK
Description		regulatory factor X5	regulatory factor X associated ankyrin containing protein
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GO Annotations	Cellular Component	Chromatin RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm Cytosol Intercellular Bridge RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Ras Protein Signal Transduction Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Bare lymphocyte syndrome (BLS) type2 Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency	Bare lymphocyte syndrome (BLS) type2 Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS		Body mass index ( 26426971)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: APP CIITA HDAC2 RFXANK RFXAP	6 interacting genes: CIITA HDAC4 HDAC5 RAF1 RFX5 RFXAP
Entrez ID		5993	8625
HPRD ID		03517	04435
Ensembl ID		ENSG00000143390	ENSG00000064490
Uniprot IDs		P48382	A0A024R7M1 A0A024R7P0 O14593
PDB IDs		2KW3 3V30	3UXG 3V30 6MEW
Enriched GO Terms of Interacting Partners?
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