USO1 and YKT6

Data Source:
BioGRID (biochemical)
HPRD (in vivo)

		USO1	YKT6
Description		USO1 vesicle transport factor	YKT6 v-SNARE homolog
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GO Annotations	Cellular Component	Golgi Membrane Fibrillar Center Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Perinuclear Region Of Cytoplasm	Golgi Membrane Cytoplasm Mitochondrion Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Integral Component Of Plasma Membrane Transport Vesicle Cytoplasmic Vesicle Membrane SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Neuronal Cell Body Apical Dendrite Basal Dendrite
	Molecular Function	RNA Binding Protein Binding Cadherin Binding	SNAP Receptor Activity Protein-cysteine S-palmitoyltransferase Activity Cadherin Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Small GTPase Mediated Signal Transduction Secretory Granule Localization Transcytosis COPII Vesicle Coating Golgi Vesicle Docking Vesicle Fusion With Golgi Apparatus Membrane Fusion Regulation Of Cellular Response To Insulin Stimulus	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Docking Involved In Exocytosis Protein Transport Protein Phosphopantetheinylation Retrograde Transport, Endosome To Golgi Membrane Fusion
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport	COPII-mediated vesicle transport COPI-mediated anterograde transport Intra-Golgi traffic
Drugs
Diseases
GWAS		Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763)	Birth weight ( 31043758 27680694) Blood sugar levels ( 29403010) Fasting plasma glucose ( 28270201) Hemoglobin A1c levels ( 29403010) HOMA-B (corrected for HOMA-IR) ( 30369944) Offspring birth weight ( 31043758) Pulse pressure ( 27841878) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Type 2 diabetes ( 30054458)
Interacting Genes		25 interacting genes: AKAP9 BET1L C1orf94 CASP3 CASP8 CSNK2B DUSP12 EEA1 GABPB1 GAK GBF1 GOLGA2 GOLGB1 GOSR1 GOSR2 NSF PHYKPL PLCG1 RAB1A RPL9 SCFD1 STX5 STXBP1 XPO7 YKT6	3 interacting genes: BET1L HSPA9 USO1
Entrez ID		8615	10652
HPRD ID		09135	16205
Ensembl ID		ENSG00000138768	ENSG00000106636
Uniprot IDs		O60763	A4D2J0 O15498
PDB IDs		2W3C	6J74 6J7F 6J7X
Enriched GO Terms of Interacting Partners?
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