YKT6 and USO1

Data Source:
BioGRID (biochemical)
HPRD (in vivo)

		YKT6	USO1
Description		YKT6 v-SNARE homolog	USO1 vesicle transport factor
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Integral Component Of Plasma Membrane Transport Vesicle Cytoplasmic Vesicle Membrane SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Neuronal Cell Body Apical Dendrite Basal Dendrite	Golgi Membrane Fibrillar Center Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	SNAP Receptor Activity Protein-cysteine S-palmitoyltransferase Activity Cadherin Binding	RNA Binding Protein Binding Cadherin Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Docking Involved In Exocytosis Protein Transport Protein Phosphopantetheinylation Retrograde Transport, Endosome To Golgi Membrane Fusion	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Small GTPase Mediated Signal Transduction Secretory Granule Localization Transcytosis COPII Vesicle Coating Golgi Vesicle Docking Vesicle Fusion With Golgi Apparatus Membrane Fusion Regulation Of Cellular Response To Insulin Stimulus
Pathways		COPII-mediated vesicle transport COPI-mediated anterograde transport Intra-Golgi traffic	Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport
Drugs
Diseases
GWAS		Birth weight ( 31043758 27680694) Blood sugar levels ( 29403010) Fasting plasma glucose ( 28270201) Hemoglobin A1c levels ( 29403010) HOMA-B (corrected for HOMA-IR) ( 30369944) Offspring birth weight ( 31043758) Pulse pressure ( 27841878) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Type 2 diabetes ( 30054458)	Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763)
Interacting Genes		3 interacting genes: BET1L HSPA9 USO1	25 interacting genes: AKAP9 BET1L C1orf94 CASP3 CASP8 CSNK2B DUSP12 EEA1 GABPB1 GAK GBF1 GOLGA2 GOLGB1 GOSR1 GOSR2 NSF PHYKPL PLCG1 RAB1A RPL9 SCFD1 STX5 STXBP1 XPO7 YKT6
Entrez ID		10652	8615
HPRD ID		16205	09135
Ensembl ID		ENSG00000106636	ENSG00000138768
Uniprot IDs		A4D2J0 O15498	O60763
PDB IDs		6J74 6J7F 6J7X	2W3C
Enriched GO Terms of Interacting Partners?
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