SMIM3 and MS4A3

Data Source:
BioGRID (two hybrid)

		SMIM3	MS4A3
Description		small integral membrane protein 3	membrane spanning 4-domains A3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process		Neutrophil Degranulation Regulation Of Cell Cycle
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)	Alzheimer's disease ( 24755620) Vitamin B12 levels ( 22367966)
Interacting Genes		52 interacting genes: ASGR2 ATP1B4 ATP6V0C BNIP3 BSCL2 BTNL9 CD53 CD79A CD82 CLDN11 CLDN5 CLDN8 CLEC17A CLEC7A CNIH1 CNIH3 EBP EMP1 EMP3 ERGIC3 FNDC9 GIMAP5 GPR42 IFNGR2 KIR3DL3 LPAR6 LSMEM2 LZTS2 MAL MS4A3 PDCD1LG2 PLP1 PMP22 PNMA1 PSCA RPRM SEC22A SFTPC SGCB SGCZ SLC22A1 SLC38A1 SMCO4 SPACA1 STX1A TEX264 TM4SF18 TMEM182 TMEM218 TMEM31 TRIM14 ZFPL1	38 interacting genes: ADIPOQ ATP6V0B BMP10 BNIP3 C4orf3 CCDC167 CD53 CD72 CDKN3 CLDN1 CLDN6 EFNA5 EMP3 ERG28 IFITM3 IGFBP5 MS4A13 NKG7 PLP1 PLPP6 SEC22A SGTA SLC22A14 SLC5A4 SMCO4 SMIM3 STX8 TEX264 TM4SF18 TMBIM6 TMEM107 TMEM140 TMEM182 TMEM218 TMEM239 VKORC1L1 YIPF6 ZFPL1
Entrez ID		85027	932
HPRD ID		12212	09403
Ensembl ID		ENSG00000256235	ENSG00000149516
Uniprot IDs		Q9BZL3	Q96HJ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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