MS4A3 and VKORC1L1

Data Source:
BioGRID (two hybrid)

		MS4A3	VKORC1L1
Description		membrane spanning 4-domains A3	vitamin K epoxide reductase complex subunit 1 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Quinone Binding
	Biological Process	Neutrophil Degranulation Regulation Of Cell Cycle	Peptidyl-glutamic Acid Carboxylation Cellular Response To Oxidative Stress Vitamin K Metabolic Process
Pathways		Neutrophil degranulation	Metabolism of vitamin K
Drugs			Menadione
Diseases
GWAS		Alzheimer's disease ( 24755620) Vitamin B12 levels ( 22367966)	Calcium levels ( 24068962) Corneal structure ( 23291589) Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 30591961) Neutrophil count ( 32888494)
Interacting Genes		38 interacting genes: ADIPOQ ATP6V0B BMP10 BNIP3 C4orf3 CCDC167 CD53 CD72 CDKN3 CLDN1 CLDN6 EFNA5 EMP3 ERG28 IFITM3 IGFBP5 MS4A13 NKG7 PLP1 PLPP6 SEC22A SGTA SLC22A14 SLC5A4 SMCO4 SMIM3 STX8 TEX264 TM4SF18 TMBIM6 TMEM107 TMEM140 TMEM182 TMEM218 TMEM239 VKORC1L1 YIPF6 ZFPL1	11 interacting genes: AQP6 CISD2 ERGIC3 GORAB GPX8 MRM1 MS4A3 MTIF3 PCYT1A PCYT1B TMEM80
Entrez ID		932	154807
HPRD ID		09403	12312
Ensembl ID		ENSG00000149516	ENSG00000196715
Uniprot IDs		Q96HJ5	A8K0F7 Q8N0U8
PDB IDs
Enriched GO Terms of Interacting Partners?
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