TRIM51 and RNF40

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRIM51	RNF40
Description		tripartite motif-containing 51	ring finger protein 40
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytosol Membrane Extrinsic Component Of Membrane HULC Complex Neuron Projection Axon Terminus
	Molecular Function	Zinc Ion Binding Ubiquitin Protein Ligase Activity	MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Syntaxin-1 Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Regulation Of Gene Expression Protein Ubiquitination Innate Immune Response	Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Histone Monoubiquitination Protein Ubiquitination Histone H2B Ubiquitination Response To Peptide Hormone Negative Regulation Of MRNA Polyadenylation Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Polyubiquitination Positive Regulation Of Histone H2B Ubiquitination
Pathways			E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 30563984) Pelvic organ prolapse (moderate/severe) ( 26545240)	Immunoglobulin light chain (AL) amyloidosis ( 28025584)
Interacting Genes		3 interacting genes: MAGEA11 RNF40 SPRY2	26 interacting genes: AMOTL2 ATM CCDC146 CDC73 DISC1 DUSP29 EEF1D ITSN1 KIF11 MEOX2 MSL1 MTNR1B NCBP1 NINL RB1 RNF20 SFR1 TRIM51 UBE2A UBE2B UBE2D2 UBE2E1 UBE2I UBE2L6 ZCCHC12 ZNF451
Entrez ID		84767	9810
HPRD ID		10282	07411
Ensembl ID		ENSG00000124900	ENSG00000103549
Uniprot IDs		Q9BSJ1	A8K6K1 O75150
PDB IDs
Enriched GO Terms of Interacting Partners?
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