SORBS2 and SOCS7

Data Source:
BioGRID (two hybrid)

		SORBS2	SOCS7
Description		sorbin and SH3 domain containing 2	suppressor of cytokine signaling 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Focal Adhesion Actin Cytoskeleton Apical Plasma Membrane Z Disc Lamellipodium Perinuclear Region Of Cytoplasm	Nucleus Cytosol Plasma Membrane Phosphatidylinositol 3-kinase Complex
	Molecular Function	RNA Binding Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Anchor Activity Structural Constituent Of Muscle	Protein Binding SH3 Domain Binding 1-phosphatidylinositol-3-kinase Regulator Activity
	Biological Process	Actin Filament Organization Notch Signaling Pathway Biological_process Cell Growth Involved In Cardiac Muscle Cell Development	Biological_process Negative Regulation Of Signal Transduction Protein Ubiquitination Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphorylation
Pathways
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 31014085) Coronary artery disease ( 33020668) Cytokine and corticosteroid-stimulated IL-6 production ( 25896417) Cytokine-stimulated IL-6 production ( 25896417) Height ( 31562340) Short-term memory (digit-span task) ( 30741946) Uterine fibroid size (maximum volume) ( 30196971) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Ovarian cancer ( 23535730)
Interacting Genes		45 interacting genes: ABI1 ABL1 ABL2 ACTN1 ACTN4 ADAM15 AFDN AKT1 AKT2 ATPAF2 CBL CBLB DLGAP1 DLGAP2 DLGAP4 EFS EGFR EIF3H FAT1 FLOT1 GOLGA2 MDM2 NCK2 NR1H2 PAK1 PAK2 PALLD PKM PTK2B PTPN12 RPL9 SEMA6A SH2D4A SH3RF1 SOCS7 SYNJ1 TEPSIN TRAF4 VCL VPS37C WAS WASF1 WASL YWHAE YWHAZ	26 interacting genes: CYSRT1 DAB1 EGFR EXOSC8 GAS2L2 GRB2 HSPB8 IRS2 IRS4 LENG8 MDFI MISP NCK1 NCK2 NSMF OSTF1 PIK3R1 PIK3R2 PLCG1 SH3RF1 SORBS2 SORBS3 TNS2 TUBA1A TUBB4B YES1
Entrez ID		8470	30837
HPRD ID		12473	12299
Ensembl ID		ENSG00000154556	ENSG00000274211
Uniprot IDs		B7Z3D7 B7Z997 O94875	O14512
PDB IDs		5VEI
Enriched GO Terms of Interacting Partners?
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