SOCS7 and GAS2L2

Data Source:
BioGRID (two hybrid)

		SOCS7	GAS2L2
Description		suppressor of cytokine signaling 7	growth arrest specific 2 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Phosphatidylinositol 3-kinase Complex	Cytoplasm Actin Filament Plasma Membrane Microtubule Plus-end Ciliary Basal Body
	Molecular Function	Protein Binding SH3 Domain Binding 1-phosphatidylinositol-3-kinase Regulator Activity	G-protein Alpha-subunit Binding Protein Binding Microtubule Binding Cytoskeletal Anchor Activity Actin Filament Binding
	Biological Process	Biological_process Negative Regulation Of Signal Transduction Protein Ubiquitination Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Phosphatidylinositol Phosphorylation	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Actin Crosslink Formation Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Protein Localization To Microtubule Plus-end
Pathways
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
Interacting Genes		26 interacting genes: CYSRT1 DAB1 EGFR EXOSC8 GAS2L2 GRB2 HSPB8 IRS2 IRS4 LENG8 MDFI MISP NCK1 NCK2 NSMF OSTF1 PIK3R1 PIK3R2 PLCG1 SH3RF1 SORBS2 SORBS3 TNS2 TUBA1A TUBB4B YES1	36 interacting genes: ABI2 BANP C7orf57 CCNDBP1 DISC1 DNAAF6 EFHC1 GOLGA2 GOLGA6L9 HMBOX1 HOOK2 HSF2BP JADE2 KCTD7 LHX3 LNX1 LRP2BP MAPRE1 MAPRE2 MAPRE3 MID2 MORN5 MTUS2 NAP1L1 PAX6 PICK1 PPP1R13B PRKAR1B RORB SAT1 SNW1 SOCS7 TFIP11 TRIM27 WWP2 ZRANB1
Entrez ID		30837	246176
HPRD ID		12299	11000
Ensembl ID		ENSG00000274211	ENSG00000270765
Uniprot IDs		O14512	Q8NHY3
PDB IDs
Enriched GO Terms of Interacting Partners?
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