LCOR and BIRC7

Data Source:
BioGRID (two hybrid)

		LCOR	BIRC7
Description		ligand dependent nuclear receptor corepressor	baculoviral IAP repeat containing 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol
	Molecular Function	RNA Polymerase II Transcription Corepressor Binding DNA Binding Transcription Corepressor Activity Protein Binding Estrogen Receptor Binding Histone Deacetylase Binding Histone Methyltransferase Binding Ubiquitin-specific Protease Binding	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cellular Response To Estradiol Stimulus	Lens Development In Camera-type Eye Apoptotic Process Activation Of JUN Kinase Activity Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Regulation Of Cell Cycle Regulation Of Natural Killer Cell Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Simvastatin-induced myopathy ( 31220337) Waist circumference ( 28552196)
Interacting Genes		13 interacting genes: AR BIRC7 CEP70 ESR1 GOLGA2 HDAC1 HDAC3 HDAC4 HDAC6 KLF6 RORB TRAF1 VDR	37 interacting genes: AURKC BOLA1 BOLA2 BOLA2B CASP3 CASP7 CASP9 DDX6 DIABLO FAM124B GTF2A1 HTRA2 KANK2 LCOR LMO4 NTAQ1 PHF1 POLR1C PRR35 PSMB1 PTCD3 QARS1 SOX5 TEPSIN TLE5 TNPO2 TSGA10IP TTPA UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2I UBE2K USP2 VPS37C XAF1
Entrez ID		84458	79444
HPRD ID		07609	05761
Ensembl ID		ENSG00000196233	ENSG00000101197
Uniprot IDs		Q96JN0	Q96CA5
PDB IDs		2COB	1OXN 1OXQ 1OY7 1TW6 2I3H 2I3I 3F7G 3F7H 3F7I 3GT9 3GTA 3UW5 4AUQ
Enriched GO Terms of Interacting Partners?
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