MED10 and MOB4

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MED10	MOB4
Description		mediator complex subunit 10	MOB family member 4, phocein
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Chromatin Nucleoplasm Mediator Complex	Cytoplasm Golgi Apparatus Golgi Cisterna Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Metal Ion Binding
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			Allergic rhinitis ( 31361310) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Schizophrenia ( 29483656) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		12 interacting genes: ABI2 ARHGDIG ESR1 ESR2 FUCA1 HNF4A KDM4B MOB4 NAP1L1 PEBP1 SYCE1L TRIM45	31 interacting genes: ARHGEF15 CCDC85B CRMP1 DNM1 EGFR EGLN2 ELK1 EPS15 FADD FBLN1 GDF9 KIDINS220 LATS1 LATS2 LRIF1 MCM2 MED10 MED31 MYL6 MYO9B NME2 PAICS PLEKHM1 PTPRS RAPGEF2 SCMH1 SETDB1 STK11 STK3 THAP4 UBE2V2
Entrez ID		84246	25843
HPRD ID		14680	10165
Ensembl ID		ENSG00000133398	ENSG00000115540
Uniprot IDs		Q9BTT4	A0A024R3X9 Q9Y3A3
PDB IDs			5YF4
Enriched GO Terms of Interacting Partners?
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