MED10 and FUCA1

Data Source:
BioGRID (two hybrid)

		MED10	FUCA1
Description		mediator complex subunit 10	alpha-L-fucosidase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Chromatin Nucleoplasm Mediator Complex	Extracellular Region Cytoplasm Lysosome Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity	Alpha-L-fucosidase Activity Protein Binding
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II	Fucose Metabolic Process Glycosaminoglycan Catabolic Process Glycoside Catabolic Process Glycolipid Catabolic Process Neutrophil Degranulation
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Neutrophil degranulation Reactions specific to the complex N-glycan synthesis pathway
Drugs
Diseases			Fucosidosis
GWAS			Arterial stiffness index ( 31235810) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		12 interacting genes: ABI2 ARHGDIG ESR1 ESR2 FUCA1 HNF4A KDM4B MOB4 NAP1L1 PEBP1 SYCE1L TRIM45	7 interacting genes: APP BARD1 CIB1 MED10 PAXIP1 UBQLN2 VAV2
Entrez ID		84246	2517
HPRD ID		14680	01974
Ensembl ID		ENSG00000133398	ENSG00000179163
Uniprot IDs		Q9BTT4	B5MDC5 P04066
PDB IDs
Enriched GO Terms of Interacting Partners?
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