SPNS1 and CCR9

Data Source:
BioGRID (two hybrid)

		SPNS1	CCR9
Description		sphingolipid transporter 1 (putative)	C-C motif chemokine receptor 9
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Lysosomal Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface
	Molecular Function	Protein Binding Transmembrane Transporter Activity	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Lipid Transport Transmembrane Transport	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs			Vercirnon
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Educational attainment ( 25201988)	Celiac disease ( 20190752) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)
Interacting Genes		8 interacting genes: ADORA2A BCL2 BCL2L1 BDKRB2 CCR8 CCR9 CHRM5 HTR2C	19 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TRPM4 TSPAN7 TTYH1 YWHAE
Entrez ID		83985	10803
HPRD ID		11599	09200
Ensembl ID		ENSG00000169682	ENSG00000173585
Uniprot IDs		A0A024QZ93 Q9H2V7	B2R734 P51686
PDB IDs			5LWE
Enriched GO Terms of Interacting Partners?
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