KRTAP3-1 and HR

Data Source:
BioGRID (two hybrid)

		KRTAP3-1	HR
Description		keratin associated protein 3-1	HR lysine demethylase and nuclear receptor corepressor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Histone Deacetylase Complex Chromatin Nucleoplasm
	Molecular Function	Structural Molecule Activity Protein Binding	Transcription Coregulator Activity Protein Binding Oxidoreductase Activity Chromatin DNA Binding Histone Demethylase Activity (H3-K9 Specific) Metal Ion Binding
	Biological Process	Keratinization	Regulation Of Transcription By RNA Polymerase II Histone H3-K9 Demethylation
Pathways		Keratinization
Drugs
Diseases			Atrichia with papular lesions Localized autosomal recessive hypotrichosis Marie-Unna hereditary hypotrichosis (MUHH)
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		82 interacting genes: ADAM12 AGXT ANAPC11 BMP7 C20orf85 CDKN1A CELA2B CERK CFP CNNM3 CREB5 CTRC CYSRT1 DMRT3 DOCK2 FAM168A FAM222B FOXH1 FRS3 GATA2 GNE GPS2 GSTP1 HCK HEY2 HOXB9 HR HSF4 IL16 ITGB4 KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP6-1 KRTAP9-3 KRTAP9-8 LCE1B LCE2B LCE3A LCE3D LCE4A LCE5A LMO4 LRRC41 MAPKBP1 MRPL40 MYPOP NOTCH2NLA NTAQ1 OTX1 PATZ1 PCSK5 PHLDA1 PKIB PLSCR4 POLR1C PPP1R32 PTPMT1 PVR RBPMS RECK REEP6 RNF44 SAMD7 SMARCC1 SPAG8 TEKT3 TEX37 TLX3 TNS2 VASN VENTX VGLL3 WDR25 YPEL3 ZFHX2 ZNF414 ZNF446	35 interacting genes: AMMECR1 ATP23 C11orf1 C19orf54 CNFN CYSRT1 FAM168A GEMIN4 HDAC1 HDAC3 HDAC5 HMGB1 HOXA1 INCA1 KLHL20 KRTAP11-1 KRTAP13-2 KRTAP15-1 KRTAP3-1 KRTAP3-3 KRTAP6-3 MGAT5B PLA2G10 PRKCA RARA RARB RBP3 SPAG8 SPRY3 TBL1X TRIM27 TSC1 VDR YPEL3 ZMYND12
Entrez ID		83896	55806
HPRD ID		13937	03808
Ensembl ID		ENSG00000212901	ENSG00000168453
Uniprot IDs		Q9BYR8	O43593
PDB IDs
Enriched GO Terms of Interacting Partners?
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