Wiki-Pi
About
Search
Browse
People
Updates
Search
H2AC20 and USP22
Data Source:
BioGRID
(enzymatic study)
H2AC20
USP22
Description
H2A clustered histone 20
ubiquitin specific peptidase 22
Image
No pdb structure
GO Annotations
Cellular Component
Nucleosome
Nucleus
Extracellular Exosome
SAGA Complex
Nucleoplasm
SAGA-type Complex
Molecular Function
Molecular_function
DNA Binding
Protein Heterodimerization Activity
Transcription Coactivator Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Cysteine-type Peptidase Activity
Zinc Ion Binding
H4 Histone Acetyltransferase Activity
Enzyme Binding
Nuclear Receptor Coactivator Activity
Biological Process
Chromatin Silencing
Biological_process
Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Embryo Development Ending In Birth Or Egg Hatching
Histone Ubiquitination
Histone Deubiquitination
Protein Deubiquitination
Protein Phosphopantetheinylation
Histone H4 Acetylation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Mitotic Cell Cycle
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
HDACs deacetylate histones
HATs acetylate histones
HATs acetylate histones
RMTs methylate histone arginines
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
UCH proteinases
Ub-specific processing proteases
Metalloprotease DUBs
Deposition of new CENPA-containing nucleosomes at the centromere
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Inhibition of DNA recombination at telomere
Amyloid fiber formation
HATs acetylate histones
Ub-specific processing proteases
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Mosquito bite size (
28199695
)
Interacting Genes
74 interacting genes:
ANP32A
APP
ATXN7L3
BAP1
BARD1
BMI1
BRCA1
CDY1
CRP
CSTF1
CTCFL
DDB2
DNMT3L
EIF2AK2
EP300
ESR1
FBL
GATAD2A
GATAD2B
H2BC1
H2BC21
H3C1
H4C1
H4C14
HAT1
HDAC2
KAT2A
KAT2B
KAT5
KAT7
MSL2
MYSM1
NAA40
NAP1L4
NCAPH
NCL
NPM1
PARP10
PBRM1
PELP1
POT1
PRMT5
PRMT7
RAG1
RBBP4
RCC1
RNF168
RNF2
RNF20
RNF8
SART3
SIRT7
SSRP1
STK38
TAF15
TAF1A
TAF1B
TCF20
TRIM37
TSPY1
TSSK6
UBC
UBE2B
UBR2
UIMC1
USP10
USP12
USP16
USP2
USP22
USP46
USP51
USP7
USP8
17 interacting genes:
AASDHPPT
ATXN7
ATXN7L3
BAG4
CD274
H2AC20
H2BC21
HEXA
MRPL10
MRPL44
MTUS2
MYC
PSME1
PTGS2
RCAN1
SCFD1
UBC
Entrez ID
8338
23326
HPRD ID
09107
19411
Ensembl ID
ENSG00000184260
ENSG00000124422
Uniprot IDs
Q16777
Q9UPT9
PDB IDs
6Y5E
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?