USP11 and DECR2

Data Source:
BioGRID (two hybrid)

		USP11	DECR2
Description		ubiquitin specific peptidase 11	2,4-dienoyl-CoA reductase 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytosol	Peroxisomal Membrane Cytosol
	Molecular Function	RNA Polymerase II Transcription Corepressor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding	Protein Binding 2,4-dienoyl-CoA Reductase (NADPH) Activity Trans-2-enoyl-CoA Reductase (NADPH) Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Viral Process Protein Deubiquitination Protein Phosphopantetheinylation	Protein Targeting To Peroxisome Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Pathways		Association of TriC/CCT with target proteins during biosynthesis Ub-specific processing proteases	Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS			Body mass index ( 26426971) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		21 interacting genes: BMI1 BRCA2 CBX8 CDKN1A DECR2 EIF4B LIMS1 LLGL1 MBD3 MTA2 PCGF2 PML RANBP9 RELB RNF2 RPS6KB1 SETDB1 SUMO2 TBL3 TP53 UBC	11 interacting genes: APP C14orf119 EP300 NEDD4L OSGIN1 PEX5 TRIM55 TRIM63 UBC USP11 VPS26C
Entrez ID		8237	26063
HPRD ID		02081	16789
Ensembl ID		ENSG00000102226	ENSG00000242612
Uniprot IDs		B4DGK3 P51784	Q9NUI1
PDB IDs		4MEL 5OK6	4FC6 4FC7
Enriched GO Terms of Interacting Partners?
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