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SYMPK and MIRLET7E
Data Source:
BioGRID
(unspecified method)
SYMPK
MIRLET7E
Description
symplekin
microRNA let-7e
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Cytoskeleton
Plasma Membrane
Bicellular Tight Junction
Nuclear Body
Nuclear Stress Granule
Extracellular Space
Molecular Function
Protein Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
MRNA Splicing, Via Spliceosome
Termination Of RNA Polymerase II Transcription
MRNA Polyadenylation
MRNA Export From Nucleus
Cell Adhesion
MRNA 3'-end Processing
Negative Regulation Of Protein Binding
Positive Regulation Of Protein Dephosphorylation
Negative Regulation Of Interleukin-6 Production
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Interleukin-6-mediated Signaling Pathway
Negative Regulation Of Receptor Signaling Pathway Via STAT
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Negative Regulation Of Signaling Receptor Activity
Pathways
Transport of Mature mRNA Derived from an Intronless Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Asthma (
31959851
)
Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) (
30940143
)
Colon cancer (
28295283
)
Colorectal cancer (
28295283
)
Coronary artery disease (
29212778
)
Eosinophil counts (
32888494
27863252
)
Eosinophil percentage of white cells (
32888494
)
Interacting Genes
45 interacting genes:
CSTF2
HSF1
HTT
MIR1-2
MIR107
MIR128-2
MIR138-2
MIR155
MIR15B
MIR16-2
MIR17
MIR18A
MIR199A1
MIR19A
MIR19B1
MIR19B2
MIR200C
MIR20B
MIR21
MIR214
MIR25
MIR29A
MIR34A
MIR363
MIR7-2
MIR9-1
MIR9-3
MIR92A1
MIR92A2
MIR93
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7D
MIRLET7E
MIRLET7G
MIRLET7I
RIN3
SUMO2
TOP1
TRIM55
TRIM63
UBE2I
YBX3
105 interacting genes:
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC40
CDC5L
CELF1
CHERP
CPSF1
CRTAP
DARS1
DDX1
DDX21
DDX23
DDX3X
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ERAL1
FAM98A
FAM98B
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PLRG1
PRMT1
PTBP1
PUF60
PUM1
PUM2
PURA
QARS1
RARS1
RBFOX2
RBM10
RBM14
RBM4
RBM47
RBM5
RTCB
SART3
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
TUT7
U2SURP
UPF1
UTP20
XAB2
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
8189
406887
HPRD ID
09090
Ensembl ID
ENSG00000125755
ENSG00000198972
Uniprot IDs
A0A024R0R6
Q92797
PDB IDs
3O2Q
3O2S
3O2T
3ODR
3ODS
4H3H
4H3K
6V4X
Enriched GO Terms of Interacting Partners
?
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