YEATS4 and TACC1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		YEATS4	TACC1
Description		YEATS domain containing 4	transforming acidic coiled-coil containing protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Matrix Nuclear Membrane NuA4 Histone Acetyltransferase Complex	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Membrane Midbody
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding Lysine-acetylated Histone Binding Modification-dependent Protein Binding	Protein Binding Nuclear Receptor Binding Estrogen Receptor Binding Nuclear Receptor Coactivator Activity Glucocorticoid Receptor Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Mitotic Cell Cycle Cytoskeleton Organization Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Population Proliferation Cerebral Cortex Development Positive Regulation Of Transcription, DNA-templated Cell Division
Pathways		HATs acetylate histones Activation of the TFAP2 (AP-2) family of transcription factors
Drugs
Diseases
GWAS		Complete remission in asthma ( 29786918) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Height ( 31562340 18391951) Metabolite levels ( 23823483) Response to antidepressants (symptom remission) ( 29160301) Response to diuretic therapy ( 18591461) Response to SSRI in MDD or conscientiouness ( 29559929) Thyroid stimulating hormone levels ( 32769997)	Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)
Interacting Genes		17 interacting genes: ANKK1 CEP162 FRMD4A GTF2F2 H3C1 MLLT10 MRGBP MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B TPM1 TRIM54	20 interacting genes: AURKA AURKB BTRC ERCC4 FAM50B HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 THRA YEATS4 ZFHX3 ZNF48
Entrez ID		8089	6867
HPRD ID		03666	10391
Ensembl ID		ENSG00000127337	ENSG00000147526
Uniprot IDs		F8W0J4 O95619	E7EVI4 O75410 Q5HYH0
PDB IDs		5VNA 5VNB 5XTZ 5Y8V
Enriched GO Terms of Interacting Partners?
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