TACC1 and MEMO1

Data Source:
BioGRID (two hybrid, two hybrid)

		TACC1	MEMO1
Description		transforming acidic coiled-coil containing protein 1	mediator of cell motility 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Membrane Midbody	Nucleus Cytosol
	Molecular Function	Protein Binding Nuclear Receptor Binding Estrogen Receptor Binding Nuclear Receptor Coactivator Activity Glucocorticoid Receptor Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Population Proliferation Cerebral Cortex Development Positive Regulation Of Transcription, DNA-templated Cell Division	Regulation Of Microtubule-based Process Regulation Of Cell Motility
Pathways			ERBB2 Regulates Cell Motility
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)	Male-pattern baldness ( 28196072) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		20 interacting genes: AURKA AURKB BTRC ERCC4 FAM50B HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 THRA YEATS4 ZFHX3 ZNF48	17 interacting genes: CAMTA2 CT55 DDIT4L DISC1 EMILIN3 GGA2 LNX1 LZTS2 RBM45 REL RFX6 TACC1 TCF4 TRIM27 TRIP6 ZBTB22 ZNF655
Entrez ID		6867	51072
HPRD ID		10391	12814
Ensembl ID		ENSG00000147526	ENSG00000162959
Uniprot IDs		E7EVI4 O75410 Q5HYH0	A8K3Y8 Q9Y316
PDB IDs			3BCZ 3BD0
Enriched GO Terms of Interacting Partners?
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